Manchester City boss Pep Guardiola brought in two big summer signings this summer, with midfielder Rodrigo joining for £62.8m from Atletico Madrid and Joao Cancelo making the move to the Ethiad for €30m (£27.5m) from Juventus, which saw Danilo go in the opposite direction.
And De Bruyne feels his manager will find it difficult to give all the players in the squad enough minutes to keep everyone happy.
“It’s probably impossible,” De Bruyne said. “We already know that.
“For him, he’s going to get questions after every game. We’re going to get questions if we don’t play. We’ve got used to it I think.
City made a fantastic start to their Premier League campaign with a 5-0 victory over West Ham but were held to a 2-2 draw with Tottenham on Saturday.
However, despite dropping points at home to Spurs, De Bruyne is pleased with how they performed in the game.
City ended the game having taken 30 shots at goals with 10 finding the target, compared to Tottenham who only managed three shots at goal with two on target.
And despite Spurs showing their efficacy in front of goal, De Bruyne felt the Sky Blues deserved to come away with all three points from the clash.
“I think the way we performed in the first three games we saw the same team,” the Belgium international added. “We went all out.
“In the end we didn’t win against Tottenham, but we deserved to and the way we played was like always.
“I’m very happy with the team’s performance at this stage of the season.”
City became the first men’s team to win the domestic treble last season despite De Bruyne only managing to make 19 Premier League appearances in the campaign, as he struggled with injuries.
However, the 28-year-old feels staying in every completion this season could be the key to Guardiola being able to give his entire squad playing time.
“There’re always moments when you want to play and you’re unhappy, but then you try to act normal and be there for the team,” he said.
“That’s why we want to compete in all competitions so there’re enough games for everyone.
“From September, we will play two or three times a week.”